Forensic auditing of the Duke Blue Devils versus William and Mary Tribe NCAAF fixture reveals an extremely high spread environment at 43.5 points. While Duke exhibits superior structural depth, key offensive line absences combined with a heavy ground-game reliance make a massive 43.5-point cover mathematically challenging against an FCS side that historically fights in the trenches. Market stability suggests current lines reflect public expectation, leaving a thin margin of tactical value on the underdog cover and alternative unders.